Endocrine Abstracts

Background: Prolonged exposure to excessive concentrations of GH and IGF-1 in acromegaly continues to affect patients’ appearance and negatively influences their self-evaluation, personal relations and morbidity. Besides chronic GH/IGF-1 excess could be deleterious to the brain through many mechanisms.Objectives: The aim of the study was to evaluate the influence of acromegaly on the prevalence and the severity of depressive symptoms in patients wit...